Angiolella L, Stringaro AR, Bernadis FD, Posteraro B, Bonito M, Toccacieli L, Torosantucci A, Colone M, Sanguinetti M, Cassone A, Palamara AT (2008) |
Increase of virulence and its phenotypic traits in drug-resistant strains of Candida albicans. |
Antimicrob Agents Chemother 52 |
pp. 927–936 |
antifungal drug resistance; biological properties; pathogenicity; drug-resistant strains; fluconazole; micafungin; Candida albicans; fungus; stepwise-increasing concentrations; drugs; molecular analyses; drug-resistance efflux pump; MDR1 gene; homozygous mutation; FSK1 gene; genetic modifications; growth capacity; drug-resistant strains; in vitro; pathogenicity; systemic mouse infection model; mortality; target organ invasion; vaginopathic potential; estrogen-dependent rat vaginal infection; pathogenicity; drug-resistant strains; systemic infection; biochemical changess; physiological changes; marked cellular alterations; major cell wall polysaccharides; rapid and extensive hypha formation; liquid and solid media; biofilm formation; antifungal drugs; drug family; C. albicans biology; biological properties; potential relevance; deep-seated candidiasis |
Causal medical examination and treatment of pathogenic fungal infections.
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